A torsional completion of gravity for Dirac matter fields and its applications to neutrino oscillations

In this paper, we consider the torsional completion of gravitation for an underlying background filled with Dirac fields, applying it to the problem of neutrino oscillations: we discuss the effects of the induced torsional interactions as corrections to the neutrino oscillation mechanism.Comment: 4 page

The synchrotron foreground and CMB temperature-polarization cross correlation power spectrum from the first year WMAP data

We analyse the temperature-polarization cross-correlation in the Galactic synchrotron template that we have recently developed, and between the template and CMB temperature maps derived from WMAP data. Since the polarized synchrotron template itself uses WMAP data, we can estimate residual synchrotron contamination in the CMB $C_\ell^{TE}$ angular spectrum. While $C_2^{TE}$ appears to be contamined by synchrotron, no evidence for contamination is found in the multipole range which is most relevant for the fit of the cosmological optical depth.Comment: Accepted for pubblication on MNRAS Lette

A model for sustainability science in higher education: water research, science and sustainability literacy, and community adaptive capacity

Thesis (Ph.D.) University of Alaska Fairbanks, 2013Climate change, population growth, land use changes, and a society more tightly connected at a global scale are impacting our freshwater resources and are forcing some communities to respond to their changing environment. Communities that want to plan for a more sustainable future require fundamental information about social-ecological systems, a scientifically and sustainability literate population who can use information for decision-making, and high levels of adaptive capacity (i.e., access to and ability to mobilize human, social, natural, and financial capital). Through their tripartite mission of research, education, and service, institutions of higher education can help ensure that these community needs are met. Many institutions are already answering this call by engaging in sustainability science. There is, however, a lack of insight from the field of education informing the field of sustainability science. One result of this is that conceptual and applied models for sustainability science are not fully developed. The goal of this work was to develop and test a model, based on literature and best practice, that institutions of higher education could use to inform their work in sustainability science. This work used a case study, action research approach to test the developed model to determine if the expected outcomes were achieved. Results show that the model was effective in generating knowledge about freshwater systems and in increasing student researchers' scientific and sustainability literacy. Results also show that the original model slightly increased community adaptive capacity and a refined model is offered to improve outcomes in this area. One major contribution of this work is that it puts forth a new conceptual model suggesting that sustainability science is a field of research, learning, and community engagement. Another important contribution of this research is that offers a new applied model that demonstrates how society, through its institutions of higher education, can functionally and effectively integrate research, learning, and community to work in the field of sustainability science and foster sustainability in social-ecological systems. This study is potentially transformative in suggesting new ways that institutions of higher education can address the challenge of sustainability

An empirical mass-loss law for Population II giants from the Spitzer-IRAC survey of Galactic globular clusters

The main aim of the present work is to derive an empirical mass-loss (ML) law for Population II stars in first and second ascent red giant branches. We used the Spitzer InfraRed Array Camera (IRAC) photometry obtained in the 3.6-8 micron range of a carefully chosen sample of 15 Galactic globular clusters spanning the entire metallicity range and sampling the vast zoology of horizontal branch (HB) morphologies. We complemented the IRAC photometry with near-infrared data to build suitable color-magnitude and color-color diagrams and identify mass-losing giant stars. We find that while the majority of stars show colors typical of cool giants, some stars show an excess of mid-infrared light that is larger than expected from their photospheric emission and that is plausibly due to dust formation in mass flowing from them. For these stars, we estimate dust and total (gas + dust) ML rates and timescales. We finally calibrate an empirical ML law for Population II red and asymptotic giant branch stars with varying metallicity. We find that at a given red giant branch luminosity only a fraction of the stars are losing mass. From this, we conclude that ML is episodic and is active only a fraction of the time, which we define as the duty cycle. The fraction of mass-losing stars increases by increasing the stellar luminosity and metallicity. The ML rate, as estimated from reasonable assumptions for the gas-to-dust ratio and expansion velocity, depends on metallicity and slowly increases with decreasing metallicity. In contrast, the duty cycle increases with increasing metallicity, with the net result that total ML increases moderately with increasing metallicity, about 0.1 Msun every dex in [Fe/H]. For Population II asymptotic giant branch stars, we estimate a total ML of <0.1 Msun, nearly constant with varying metallicity.Comment: 17 pages, 9 figures, in press on A&

Combined approach to define the clinical impact and decision making in asthmatics.

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New insights on the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation

Genome-wide association studies have generally failed to identify polymorphisms associated with antidepressant response. Possible reasons include limited coverage of genetic variants that this study tried to address by exome genotyping and dense imputation. A meta-analysis of Genome-Based Therapeutic Drugs for Depression (GENDEP) and Sequenced Treatment Alternatives to Relieve Depression (STAR*D) studies was performed at SNP, gene and pathway level. Coverage of genetic variants was increased compared to previous studies by adding exome genotypes to previously available genome-wide data and using the Haplotype Reference Consortium panel for imputation. Standard quality control was applied. Phenotypes were symptom improvement and remission after 12 weeks of antidepressant treatment. Significant findings were investigated in NEWMEDS consortium samples and Pharmacogenomic Research Network Antidepressant Medication Pharmacogenomic Study (PGRN-AMPS) for replication. 7,062,950 SNPs were analysed in GENDEP (n=738) and STAR*D (n=1409). rs116692768 (p=1.80e-08, ITGA9 (integrin alpha 9)) and rs76191705 (p=2.59e-08, NRXN3 (neurexin 3)) were significantly associated with symptom improvement during citalopram/escitalopram treatment. At gene level, no consistent effect was found. At pathway level, the Gene Ontology terms GO:0005694 (chromosome) and GO:0044427 (chromosomal part) were associated with improvement (corrected p=0.007 and 0.045, respectively). The association between rs116692768 and symptom improvement was replicated in PGRN-AMPS (p=0.047), while rs76191705 was not. The two SNPs did not replicate in NEWMEDS. ITGA9 codes for a membrane receptor for neurotrophins and NRXN3 is a transmembrane neuronal adhesion receptor involved in synaptic differentiation. Despite their meaningful biological rationale for being involved in antidepressant effect, replication was partial. Further studies may help in clarifying their role

Impact of bisphenol A (BPA) on early embryo development in the marine mussel Mytilus galloprovincialis: Effects on gene transcription.

Bisphenol A (BPA), a monomer used in plastic manufacturing, is weakly estrogenic and a potential endocrine disruptor in mammals. Although it degrades quickly, it is pseudo-persistent in the environment because of continual inputs, with reported concentrations in aquatic environments between 0.0005 and 12 \u3bcg/L. BPA represents a potential concern for aquatic ecosystems, as shown by its reproductive and developmental effects in aquatic vertebrates. In invertebrates, endocrine-related effects of BPA were observed in different species and experimental conditions, with often conflicting results, indicating that the sensitivity to this compound can vary considerably among related taxa. In the marine mussel Mytilus galloprovincialis BPA was recently shown to affect early development at environmental concentrations. In this work, the possible effects of BPA on mussel embryos were investigated at the molecular level by evaluating transcription of 13 genes, selected on the basis of their biological functions in adult mussels. Gene expression was first evaluated in trocophorae and D-veligers (24 and 48 h post fertilization) grown in physiological conditions, in comparison with unfertilized eggs. Basal expressions showed a general up-regulation during development, with distinct transcript levels in trocophorae and D-veligers. Exposure of fertilized eggs to BPA (10 \u3bcg/L) induced a general upregulation at 24 h pf, followed by down regulation at 48 h pf. Mytilus Estrogen Receptors, serotonin receptor and genes involved in biomineralization (Carbonic Anydrase and Extrapallial Protein) were the most affected by BPA exposure. At 48 h pf, changes in gene expression were associated with irregularities in shell formation, as shown by scanning electron microscopy (SEM), indicating that the formation of the first shelled embryo, a key step in mussel development, represents a sensitive target for BPA. Similar results were obtained with the natural estrogen 17\u3b2-estradiol. The results demonstrate that BPA and E2 can affect Mytilus early development through dysregulation of gene transcription

Late-time Light Curves of Type II Supernovae: Physical Properties of SNe and Their Environment

We present BVRIJHK band photometry of 6 core-collapse supernovae, SNe 1999bw, 2002hh, 2003gd, 2004et, 2005cs, and 2006bc measured at late epochs (>2 yrs) based on Hubble Space Telescope (HST), Gemini north, and WIYN telescopes. We also show the JHK lightcurves of a supernova impostor SN 2008S up to day 575. Of our 43 HST observations in total, 36 observations are successful in detecting the light from the SNe alone and measuring magnitudes of all the targets. HST observations show a resolved scattered light echo around SN 2003gd at day 1520 and around SN 2002hh at day 1717. Our Gemini and WIYN observations detected SNe 2002hh and 2004et, as well. Combining our data with previously published data, we show VRIJHK-band lightcurves and estimate decline magnitude rates at each band in 4 different phases. Our prior work on these lightcurves and other data indicate that dust is forming in our targets from day ~300-400, supporting SN dust formation theory. In this paper we focus on other physical properties derived from the late time light curves. We estimate 56Ni masses for our targets (0.5-14 x 10^{-2} Msun) from the bolometric lightcurve of each for days ~150-300 using SN 1987A as a standard (7.5 x 10^{-2} Msun). The flattening or sometimes increasing fluxes in the late time light curves of SNe 2002hh, 2003gd, 2004et and 2006bc indicate the presence of light echos. We estimate the circumstellar hydrogen density of the material causing the light echo and find that SN 2002hh is surrounded by relatively dense materials (n(H) >400 cm^{-3}) and SNe 2003gd and 2004et have densities more typical of the interstellar medium (~1 cm^{-3}). The 56Ni mass appears well correlated with progenitor mass with a slope of 0.31 x 10^{-2}, supporting the previous work by Maeda et al. (2010), who focus on more massive Type II SNe. The dust mass does not appear to be correlated with progenitor mass.Comment: We corrected the 56Ni mass of SN2005cs and Figures 8 (a) and 8 (c

Strong Reduction of the Field-Dependent Microwave Surface Resistance in YBCO with BaZrO_3 Inclusions

We present measurements of the magnetic field dependent microwave surface resistance in laser-ablated YBa$_2$Cu$_3$O$_{7-\delta}$ films on SrTiO$_3$ substrates. BaZrO$_3$ crystallites were included in the films using composite targets containing BaZrO$_3$ inclusions with mean grain size smaller than 1 $\mu$m. X-ray diffraction showed single epitaxial relationship between BaZrO$_3$ and YBa$_2$Cu$_3$O$_{7-\delta}$. The effective surface resistance was measured at 47.7 GHz for 60$< T <$90 K and 0$< \mu_0H <$0.8 T. The magnetic field had a very different effect on pristine YBa$_2$Cu$_3$O$_{7-\delta}$ and YBa$_2$Cu$_3$O$_{7-\delta}$/BaZrO$_3$, while for $\mu_0H=$0 only a reduction of $T_c$ in the YBa$_2$Cu$_3$O$_{7-\delta}$/BaZrO$_3$ film was observed, consistent with dc measurements. At low enough $T$, in moderate fields YBa$_2$Cu$_3$O$_{7-\delta}$/BaZrO$_3$ exhibited an intrinsic thin film resistance lower than the pure film. The results clearly indicate that BaZrO$_3$ inclusions determine a strong reduction of the field-dependent surface resistance. From the analysis of the data in the framework of simple models for the microwave surface impedance in the mixed state we argue that BaZrO$_3$ inclusions determine very steep pinning potentials.Comment: LaTeX, 6 pages, 4 figures, uses jpconf.cls and jpconf11.clo class files, talk given at EUCAS 2007, submitted to J. Phys.: Conf. Serie